Leverage Pyke's strong early game stats, potent Q/E crowd control, and W vision control to gain advantages in lane and through roaming.
As a squishy champion unable to build health, minimize deaths and always plan for safe engages and disengages using your W/E abilities.
While Pyke's power tapers off in the late game, focusing on assassinating key squishy enemy champions with your ultimate can still make you highly impactful.