In patch 14.18, Jungle Karthus was played in 40,776 games in Émeraude + tier, with a 49.88% win rate and a 2.39% pick rate. Current rank of the champion is Palier 4, and the most popular core items include , , and The most popular runes include (, , , ) for primary path and (, ) for secondary path.
Karthus strong against , , and but weak against Karthus include , , and .
Karthus performs strongest at 40+ minutes with a 52.68% win rate and weakest at 25-30 minutes with a 48.93% win rate.